STUDY OF PATHOMORPHOLOGICAL CHANGES IN THE PLACENTA AT 11-12 WEEKS OF PREGNANCY
Keywords:
trophoblast, intervillous space, placental development, placental growth factor, terminated pregnancy, preeclampsia.Abstract
The article discusses research in the field of classical morphological descriptions of
the early development of the placenta. When morphologically studying the placenta, according to
an analysis of a large amount of literature, before the ninth week of pregnancy, a restriction of
arterial communication with the villous space is detected, which leads to low oxygen tension in
the placenta. However, in the ninth week, there is a weakening of the arterial plugs, increasing the
flow of oxygen to the placenta. Studies have also shown that replacing plasma protein-A with
placental growth factor in screening for fetal trisomy and preeclampsia may improve screening
accuracy. Taken together, these studies contribute to the understanding of early placental
development and the factors influencing its normal functioning.
