Anemia in Chronic Diseases

Abstract

Anemia that occurs during infectious and inflammatory processes, non-infectious inflammatory diseases and tumors is called “anemia of chronic diseases” (ACD). With all the diversity of pathogenetic mechanisms for the development of anemia in these situations, one of the main ones is the redistribution of iron into the cells of the macrophage system, which is activated during various inflammatory (infectious and non-infectious) or tumor processes. In terms of the prevalence of ACD, they occupy 2nd place after iron deficiency anemia (IDA). The identification of ACD as a separate pathogenetic variant and awareness of it are important because of the similarity of this variant with IDA and some sideroachrestic anemias, although the essence and therapeutic approaches for these anemias are different.