http://grnjournal.us/index.php/AJPMHS/issue/feed American Journal of Pediatric Medicine and Health Sciences (2993-2149) 2024-06-27T08:18:42-04:00 Editor in Chief editor@grnjournal.us Open Journal Systems <p><strong><a href="https://portal.issn.org/resource/ISSN/2993-2149">American Journal of Pediatric Medicine and Health Sciences</a> <a href="https://portal.issn.org/resource/ISSN/2993-2149">(2993-2149 under U.S. ISSN Center</a>)</strong> - is an international, open-access, peer-reviewed online journal covering all aspects of the diagnosis, management, and prevention of disorders specific to children and adolescents, including pediatric oncology, pediatric cardiology, pediatric critical care, pediatric endocrinology, pediatric gastroenterology, hepatology and nutrition, pediatric hematology and hematological malignancies, obstetric and pediatric pharmacology, pediatric immunology, pediatric infectious diseases, pediatric nephrology, pediatric neurology, pediatric orthopedics, pediatric otolaryngology, pediatric pulmonology, pediatric surgery, pediatric urology and etc.</p> http://grnjournal.us/index.php/AJPMHS/article/view/4986 The Correlation between ABO Blood Groups and the IFN-Γ Levels in COVID 19 Infected Patients 2024-06-05T06:27:48-04:00 Oday Jawad Jasim author@gmail.co Dr. Wisam Basim Al-Tmemy author@gmail.co Marwa sadiq Husain Meshary author@gmail.co <p>This investigation was conducted in the Iraqi province of Wasit in collaboration with the microbiology units of Fairouz Hospital and Alzahraa Hospital. This study's objectives were to assess interferon (IFN)-γ serum levels and this cytokine's protective role based on the ABO blood types among SARS-CoV-2 infected individuals. Samples were gathered in the province of Wasit from various locations. It had 22 healthy individuals as a control group and 66 blood samples from Iraqi patients suffering with COVID-19. The study was carried out between January and April of 2024, with both groups' ages ranging from 14 to 72. There were three patient classifications: mild (22 patients), moderate (22 patients), and severe (22 patients). All participants' serum samples were taken, and ELISA (enzyme-linked immunosorbent assay) was used to measure the levels of cytokines using monoclonal antibodies (Anti-A, B, and D). All of these tools are easily accessible in a blood test tool set. ( AntiSera ABD Blood Grouping Reagent BIOLAB-India). The ANOVA test shows that mean level was statistically not significant difference( p-value 0.649) for concentration of interferon gamma according to the blood groups.</p> 2024-06-05T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5087 Algorithm for the Implementation of Manometry and Ph-Impedansometry in the Management of Patients with Refractory Gastroesophageal Reflux Disease 2024-06-11T07:33:27-04:00 Khodieva Ozoda Ibragimovna Author@gmail.co <p>Gastroesophageal reflux disease (GERD) is a widespread disease that has a significant impact on the quality of life of patients and is a leading risk factor for the development of esophageal adenocarcinoma. Currently, proton pump inhibitor therapy (PPI) is the basic treatment for patients with GERD, but 1/3 of patients show resistance to the prescribed therapy.</p> <p>Currently, 24-hour pH-impedancemetry and high-resolution esophageal manometry are the most informative diagnostic methods in patients resistant to PPI therapy. These methods allow timely recognition of the causes of the refractory course of GERD, differential diagnosis with other nosologies, timely correctionadminister therapy individually for each patient.</p> 2024-06-11T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5088 Treatment of Postoperative Radicular Pain Syndrome by Pulsed Radiofrequency Ablation of Spinal Ganglia 2024-06-11T07:34:52-04:00 Karim Rakhmatov Author@gmail.co <p>The article discusses the use of pulsed radiofrequency ablation (HDI) of the spinal ganglia for the treatment of postoperative radicular pain syndrome (PCBS). PCBS is a common complication after spinal surgery, often leading to chronic pain and a decrease in the quality of life of patients. HDI is a minimally invasive method that allows you to purposefully affect the nerve ganglia responsible for pain impulses, with minimal damage to the surrounding tissues. The study involved 50 patients with chronic pain that did not respond to conservative treatment. The results showed a significant reduction in pain intensity by 70% on the visual analog scale (VAS) and an improvement in the quality of life in 80% of patients. The procedure turned out to be safe, without serious complications. Thus, HDI demonstrates high efficiency and safety in the treatment of PCBS, offering a promising solution for patients suffering from chronic pain syndrome after spinal surgery.</p> 2024-06-11T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5089 Modern Approaches to the Diagnosis and Treatment of Traumatic Brain Injuries: Innovations and Prospects 2024-06-11T07:36:00-04:00 Mardanov Jamshid Dzhakhangirovich Author@gmail.co <p>The article discusses modern approaches to the diagnosis and treatment of traumatic brain injuries (TBI), with an emphasis on innovations and development prospects in this area. Traumatic brain injuries are a significant cause of disability and mortality worldwide, which underscores the need to improve their diagnosis and treatment. The paper describes the latest techniques, including neuroimaging, molecular diagnostics, and robotic rehabilitation systems, which show significant advantages over traditional approaches. Neuroimaging, such as magnetic resonance imaging (MRI) and positron emission tomography (PET), significantly improves the accuracy of diagnosis, allowing you to detect damage at an early stage. Molecular diagnostics contributes to a detailed understanding of pathological processes at the cellular level, which opens up new opportunities for personalized treatment. Robotic rehabilitation systems demonstrate high efficiency in restoring motor functions and improving the quality of life of patients. Clinical studies confirm that the integration of these innovative methods contributes to improved treatment outcomes. The conclusion of the article emphasizes the need for further research to optimize existing methods and develop new approaches that can provide more effective treatment and rehabilitation of patients with traumatic brain injuries.</p> 2024-06-11T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5114 Epidemiological Situation of Tuberculosis among Children and Adolescentsq 2024-06-12T05:43:01-04:00 Ashurov Otabek Shavkatovich author@gmail.co <p>According to a World Health Organization report, tuberculosis (tuberculosis) is the most deadly disease on the planet. It is noted that global efforts have saved 54 million people from dying from tuberculosis since 2000, but 1.6 million people died from it in 2017 alone.</p> 2024-06-12T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5115 Optimizing the Diagnosis and Prevention of Tuberculosis in Children 2024-06-12T05:46:48-04:00 Ashurov Otabek Shavkatovich author@gmail.co <p>The peak of tuberculosis infection activity in the world occurred at the end of the 20th century. Tuberculosis is recognized by WHO as a global problem causing enormous economic and biological damage. If 20' years ago there was a decrease in morbidity and mortality from tuberculosis in the world, now 1/3 j' of the population is infected with Mycobacterium tuberculosis</p> <p>The epidemiological situation of tuberculosis in different regions of the world is constantly changing as a result of the complex relationship between population movements, the number and distribution of tuberculosis patients , the socio-economic and cultural level of the population, the availability of medical care, and the prevalence of HIV infection.</p> 2024-06-12T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5116 The Influence of IL-4, IL-18, IFN-Γ AND TNF-Α Properties in Blood Plasma in HIV-Infected Children 2024-06-12T05:47:56-04:00 D. A. Karimov author@gmail.co B. H. Begmatov author@gmail.co D. F. Raimkulova author@gmail.co B. S.Ermatov author@gmail.co O. E. Melikuziyev author@gmail.co L. Y. Aladova author@gmail.co B. V.Shukurov author@gmail.co <p>Despite advancements in treatment and care, HIV infection continues to pose significant challenges, especially in pediatric populations. Children living with HIV often experience immune dysregulation and heightened inflammatory responses, leading to increased susceptibility to opportunistic infections and disease progression. Cytokines are critical signaling molecules that orchestrate the immune response and influence the pathogenesis of HIV infection (Tudela et al., 2014).</p> <p>The epidemiological situation of tuberculosis in different regions of the world is constantly changing as a result of the complex relationship between population movements, the number and distribution of tuberculosis patients , the socio-economic and cultural level of the population, the availability of medical care, and the prevalence of HIV infection</p> 2024-06-12T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5117 Diet for Chronic Kidney Disease (Overview) 2024-06-12T05:51:08-04:00 Amonov Mukhammad Komil ugli author@gmail.co <p>Chronic kidney disease (CKD) patients and their clinicians seek ways to mitigate the risk of CKD progression and its associated complications. Emerging data suggest that dietary modifications may be beneficial adjuvant approaches to reducing the risk of adverse CKD outcomes. This review focuses on several different dietary patterns, including the Dietary Approaches to Stop Hypertension and Mediterranean diets, and their kidney health benefits. We discuss how healthful dietary patterns are lower in dietary acid load and how improving diet quality may slow the progression of CKD. We also discuss some barriers that may impede socially disadvantaged individuals from following healthful diets.&nbsp; Dietary patterns low in dietary acid load might slow the progression of CKD. Current evidence suggests that a reduction in dietary acid load could be beneficial in patients with CKD, but the supremacy of any particular diet is yet to be established. Additional randomized controlled dietary interventions among CKD patients are needed to inform evidence-based recommendations, which can be tailored to an individual's preferences and ability to access healthful foods.</p> 2024-06-12T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5118 The Importance of Modern Information Technology in the Screening Process of Patients’ Involved Intreatment of Chronic Non-Communicable Diseases 2024-06-12T05:52:19-04:00 Khodjieva Gulirano Sayfullaevna author@gmail.co <p>This article describes the results of a study on the adaptation, implementation and evaluation of the effectiveness of the MyTherapy mobile application in the practice of treating chronic non-infectious diseases in order to monitor treatment and patient compliance. Based on the more pronounced positive dynamics of the therapy itself, the improvement in the quality of life indicator and the indicator of adherence to treatment, it is shown that the use of this mobile application can be a highly effective method of monitoring the therapy of chronic non-infectious diseases when used correctly.</p> 2024-06-12T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5119 Precancerous Markers in the Development of Ovarian Endometrioma 2024-06-12T05:53:25-04:00 F. Sh. Oripova author@gmail.co <p>The article contains fragments of a scientific study aimed at developing prognostic criteria for uterine leiomyoma, the authors studied cancer markers in women of reproductive age. Early diagnosis of uterine leiomyoma contributes to effective conservative and organ-preserving treatment of this disease.</p> 2024-06-12T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5120 Treatment Tactics after Relapses in Cases of Complex Treatment of Cervical Cancer 2024-06-12T05:54:41-04:00 Jurayeva Gulbaxor Alisherovna author@gmail.co Amanov Akmal Karimjonovich author@gmail.co <p>For patients with primary stage ⅣB, persistent, or recurrent cervical cancer, chemotherapy remains the standard treatment, although it is neither curative nor associated with long-term disease control. In this review, we summarized the history of treatment of recurrent cervical cancer, and the current recommendation for chemotherapy and molecular targeted therapy.This article is devoted to the tactics of treatment of cervical cancer (BBS) in cases of recurrence after complex treatment. In cases of relapse, it is important to determine and use effective treatment methods. The article examines methods for detecting relapses, what treatment strategies are used for relapses at what stage, and new treatment technologies.</p> 2024-06-12T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5179 Effect of Pomegranate Seed oil on the Urinary System 2024-06-15T05:54:18-04:00 Djuraev Shavkat Bobonatharovich Author@gmail.co Khikmatova Madina Furkatovna Author@gmail.co <p>Pomegranate seed oil, obtained by cold pressing the seeds of the fruit, has long been used in traditional medicine and is noteworthy for its potential health benefits. Regarding its effect on the urinary system, there are several aspects: Diuretic Properties: Pomegranate seed oil has mild diuretic properties, which means it may help increase urine output. This may be helpful for people suffering from swelling or discomfort associated with fluid retention. Anti-inflammatory properties: Components of pomegranate seed oil, such as phytochemicals and antioxidants, may help reduce inflammation in the urinary system. This may be especially useful for various conditions such as cystitis or other inflammatory conditions. Kidney protection: Some research suggests that the antioxidants found in pomegranate seed oil may help protect kidney tissue from damage caused by oxidative stress. This may help maintain kidney health and prevent the development of certain kidney diseases.</p> 2024-06-15T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5180 Prevention and Pathogenetic Care for Patients with Odontogenic Periostitis of the Jaws 2024-06-15T05:57:09-04:00 Makhmudov Jahongirmirzo Author@gmail.co <p>Acute odontogenic periostitis is a purulent type of the disease that causes infection of the periosteum of the alveolar process and localized inflammation in periodontal tissues. Purulent periostitis typically affects the lower jaw. Keywords: odontogenic periostitis, odontogenic inflammation, periodontitis.</p> 2024-06-15T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5181 Causes and Therapy of Inflammatory Processes in the Maxillofacial Region with Antibiotics from the Penicillin Group 2024-06-15T05:58:03-04:00 Makhmudov Jahongirmirzo Author@gmail.co <p>Currently, inflammatory processes activate various systems in the body. This article reveals the etiology and pathogenesis of odontogenic inflammatory diseases of the maxillofacial region. Special attention is paid to the aggressive course of the inflammatory process with the defeat of deep cellular spaces, accompanied by pronounced endogenous intoxication. The author analyzes the importance of the use of antibiotics from the group of penicillins in the treatment of inflammatory processes of the maxillofacial region.</p> 2024-06-15T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5188 Management of Krumiroga in Paediatrics by Ayurveda: A Review 2024-06-17T01:03:58-04:00 Dr. Anant Pawade author@gmail.co Dr. Subodh Pralhad Kele author@gmail.co Dr. Nilesh Tatyarao Gore author@gmail.co <p>Krumiroga, commonly known as worm infestation, is a prevalent health issue addressed in Ayurveda. This condition refers to the invasion of the human body by various types of parasites, leading to a spectrum of health disturbances. The Ayurvedic system offers a holistic approach to managing Krumiroga, emphasizing dietary regulations, herbal medications, and lifestyle modifications. Krumiroga is (worm infestation) is one of the most common disease encountered in day to day Paediatric practice. Helminthes are quite common and comprise a very large group of infestations and disease producing in children. Helminthiasis is prevalent globally (33% of world’s population harbours them), but is more common in developing countries with poorer personal and environmental hygiene. In Ayurvedic literatures, the word krumi is vague term used to denote tiny living being. Many Acharyas described krumis in various Samhitas in detail and they also believed that krimi also act as an etiological factor in various disease e.g. krumija shiroroga, hridroga etc. Because of the negligible side effects, the importance of ayurveda drugs has tremendously increased in the recent practice. A wide variety of ayurveda drugs possess anthelminthic activities which are naturally available in abundance.</p> 2024-06-17T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5195 Morphology of the bladder in fetuses with kidney pathology in the mother 2024-06-18T06:44:20-04:00 Yuldashev Bakhrom Sabirzhanevich author@gmail.co Ollaberganov Mardon Ismailovich author@gmail.co Karimov Rasulbek Khasanovich author@gmail.co Rajabov Odilbek Anvarbekovich author@gmail.co Kuryazov Sardor Bakhtiyorovich author@gmail.co <p><strong>Relevance of the topic. </strong>The incidence of kidney pathologies in countries around the world is increasing every year. These figures are slightly higher in Central Asian countries. The reason depends on the lifestyle of the population, climate, drinking water and many other factors. This, in turn, leads to an increase in the number of women who undergo pregnancy without kidney pathology. Fetuses with kidney pathology in mothers do not affect the organs of the urinary system, including the morphological development of the bladder. Analysis of morphometric changes during the development of the bladder in fetuses without kidney pathology and mothers with kidney pathology at different stages of gestation.</p> <p><strong>Purpose of the study</strong><strong>. </strong>Identification of morphological changes in the bladder in fetuses with kidney pathology in their mothers.</p> 2024-06-17T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5196 Description of the Dependence of Craniometric Parameters on the Severity of Myopia in Children with Myopia 2024-06-18T06:54:59-04:00 Ibragimova H. Z. author@gmail.co Rasulov H. A. author@gmail.co Eshonkulova B. D. author@gmail.co <p>According to the World Health Organization (WHO), myopia has spread to 1.6 billion people in recent years and is predicted to reach 5 billion by 2050. Carrying out a number of studies in case of dysfunction of a particular organ allows us to determine changes in special topographic areas of the musculoskeletal system against the background of diseases. Craniometry is considered one of the important sections of anthropometry, and the determination of anatomical changes in craniometric parameters is of great importance for theoretical and practical medicine. Today, craniometric studies are actively used in scientific research in otorhinolaryngology, neurology, dentistry and ophthalmology and help find reasonable solutions to the problems of these areas. One of these tasks is to find a solution for studying the formation of the eyeball with varying degrees of severity of myopia, which is the most common refractive anomaly in a growing body. There is a need in the world to determine the theories of cooperative development of organs and the topographical areas in which they are located and which of them are the main ones. In recent years, the incidence of myopia has been increasing worldwide, reaching 96% among the young population of some countries. However, in children born with myopia, little has been studied about the formation processes in the organs and systems of the growing organism, in particular, what obstacles arise in the development and growth of the orbit. Establishing parallels in the development of the organ of vision and the eyeball helps to develop measures aimed at preventing developmental defects that can be observed in postnatal ontogenesis. The prevalence of myopia among children and not always timely diagnosis can negatively affect the child’s quality of life, lead to retinal detachment and disability from childhood or early working age.</p> 2024-06-17T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5230 Effective Effect of the Drug Emfetal on the Fetus 2024-06-20T07:27:21-04:00 Axmedov Shamshod Jamshidovich Author@gmail.co <p>One of the most common hypovitaminosis in pregnant women is a deficiency of iron and folic acid, leading to anemia - a condition in which the amount of hemoglobin (the oxygen carrier in red blood cells) is reduced. Tissues damaged during childbirth heal very slowly. Severe postpartum depression, osteoporosis, caries develops, the condition of the skin and hair changes. An effective method of replenishing vitamin and mineral deficiency during pregnancy and lactation is regular intake of the Emfetal vitamin and mineral complex, containing 12 vitamins and 10 minerals. Its action is due to the effects of its constituent vitamins and minerals. Vitamins participate in metabolism as catalysts and regulators of biochemical and physiological processes. Minerals are vital elements for metabolic processes in the human body, participate in the construction of cells and tissues of the body, and in the activity of enzyme systems. Emfetal contains 3 fat-soluble (A, E and D) and 9 water-soluble vitamins (B1, B2, B5, B6, B9, B12, C, PP, H).</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5231 Treatment of Odontogenic Phlegmon of the Maxillofacial Region 2024-06-20T07:31:03-04:00 Mahmudov Jahongirmirzo Komilovich Author@gmail.co <p>Phlegmon MFA frequently presents as a condition affecting multiple pathways in the homeostasis system, including immunity, detoxification, hemostasis, rheology, etc. Gross disorders of regulation and metabolism that result in a violation of homeostasis, "disruption" of protective systems and functions, and the creation of vicious autocatalytic circles that foster the maintenance and advancement of end toxemia are the hallmarks of the development of endogenous intoxication syndrome in purulent-inflammatory diseases. The treatment of odontogenic phlegm in the maxillofacial region is the subject of this article.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5233 Modern Ideas of Morphogenesis and Mammary Glands Function in Pregnancy and Lactation Dynamics 2024-06-20T07:33:46-04:00 Khasanov Bakhtiyor Burtkhanovich Author@gmail.co <p>This article provides a brief overview of mammary gland structural and functional characteristics of a non-pregnant virgin mammal and occurring morphofunctional changes during the dynamics of pregnancy and lactation.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5234 The Role of the Mammary Gland in Ensuring Immune Homeostasis of the Fetus and Newborn 2024-06-20T07:35:33-04:00 Khasanov Bakhtiyor Burtkhanovich Author@gmail.co <p>This review presents research on structural and functional features of mammary gland parenchymal and stromal components; importance of the mammary gland in the adoptive immunity transfer to a newborn, particularly immune humoral and cellular components transmitted from mother to baby.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5235 Modern Views about Structural and Functional Features Spleen 2024-06-20T07:36:42-04:00 Khasanov Bakhtiyor Burtkhanovich Author@gmail.co <p>The spleen is a peripheral organ of the immune system, involved in hematopoiesis and is a cemetery for old red blood cells. A brief review presents the latest literature data on the structural and functional areas and cellular components of the organ and the functions they perform.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5236 Predictors in Predicting Premature Birth 2024-06-20T07:38:19-04:00 Lyalya Sarkisova Author@gmail.co <p>In accordance with the purpose and objectives of this study, we studied the course of pregnancy and childbirth in 200 women at a gestational age of 22-36 weeks. The main group consisted of 65 women with a threatened miscarriage, 40 women with preterm labor without amniotic fluid and 45 women with amniotic fluid, the control group consisted of 50 women with a physiological course of pregnancy. Immunological studies were carried out in the immunological laboratory of the Specialized Research Republican Center for Obstetrics and Gynecology.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5237 Chronic Prostatitis 2024-06-20T07:39:36-04:00 Karimov Hakimjon Rayimberdievich Author@gmail.co <p>This article contains information from local and foreign literature about the factors causing chronic prostatitis, clinical symptoms, types, complications, treatment and prevention. Information on the course, diagnosis and prevention of chronic prostatitis, acute and chronic bacterial prostatitis and chronic pelvic pain syndrome is presented.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5239 Prostatic Hyperplasia (BPH) 2024-06-20T07:40:50-04:00 Karimov Hakimjon Rayimberdievich Author@gmail.co <p>This article presents information from local and foreign sources about the disease of prostate gland hyperplasia (BPH): causative factors, symptoms, types, complications, treatment and prevention. In the diagnosis of compensated, subcompensated, decompensated and terminal stages of prostatic hyperplasia, information is provided about the patient's questionnaire, urological examination and a number of other laboratory and instrumental examination methods.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5240 Risk Factors, Prevalence and Epidemiology of Prostate Cancer 2024-06-20T07:42:12-04:00 Karimov Hakimjon Rayimberdievich Author@gmail.co <p>This article presents information from foreign sources about the factors and epidemiology of prostate cancer. Information on the importance and influence of risk factors for prostate cancer, including genetic factors, poor-quality diet, chemical drug exposure, infections, sexual activity, and ethnicity, was obtained from the National Cancer Institute (NCI) database.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5241 Mechanisms of Damage to the Gastric Mucosa in Mixed Injuries 2024-06-20T07:43:25-04:00 Soliev Abbosjon Alisher ugli Author@gmail.co <p>The article provides data on damage to the stomach in mixed injuries. Mixed injuries can lead to rupture of intra-abdominal structures, which causes bleeding and release of stomach, intestinal or bladder contents into the abdominal cavity. This can lead to peritonitis and other serious complications. Bleeding may be slight or heavy, depending on the extent of the damage. More severe injuries may result in shock, acidosis, and coagulopathy. In these cases, surgery is required.</p> <p>Late complications of abdominal trauma may include hematoma rupture, intra-abdominal abscess, intestinal obstruction or ileus, bile leak and/or biloma, and abdominal compartment syndrome. Complications of treatment may also include abscess, intestinal obstruction, abdominal compartment syndrome, and late incisional hernia. Understanding the mechanisms of damage to the gastric mucosa during mixed injuries is crucial for timely diagnosis and treatment, as well as for the prevention of complications.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5242 The Morphological Role of the Spleen under Temperature Influences 2024-06-20T07:44:39-04:00 Davronova Sh. R. Author@gmail.co Turakulov M. T. Author@gmail.co <p>The spleen is an important organ of the immune system responsible for blood filtration, involved in the development of lymphocytes and the formation of antibodies. The main functions of the spleen in the immune response, its influence on the processes of formation and activation of immunity are analyzed. The article also presents data on the influence of the spleen on the formation of memory of the immune system and its ability to adapt to new pathogens. The study of the biological role of the spleen in the processes of immunogenesis allows us to better understand the mechanisms of functioning of the immune system and unlock the potential for developing new approaches to strengthening the immune response.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5244 Risk Factors for Caries in Children 2024-06-20T07:46:22-04:00 Djalolidinova Shakhlo Djamolidinovna Author@gmail.co <p>Cariesogenic factors can be of different intensity and nature, different variants of their interaction contribute to the occurrence of caries, but the leading factor is the microflora of the oral cavity.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5246 Complications of Oral Injuries in Young Children 2024-06-20T07:47:49-04:00 Tulanova Mokhichehra Akram kizi Author@gmail.co <p>Children are restless, their desire to explore the world around them sometimes ends in tears. Abrasions, bruises, cuts, burns are not the whole list of injuries that are often found in children. Injuries to the oral cavity are also not uncommon and no less diverse. In addition to fractures and dislocations of teeth, tears, cuts and abrasions of the soft tissues of the oral cavity are often found in the practice of pediatric dentists.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5248 Analysis of the Significance of Infection in Diseases of the Urinary System 2024-06-20T07:49:02-04:00 Mamatmusaeva Fotima Shaydullaevna Author@gmail.co Raimkulova Dilnoza Farkhaddinovna Author@gmail.co Gulmurotova Dilafruz Shoymardonovna Author@gmail.co Ermatov Botir Sobirovich Author@gmail.co <p>One of the most common infections in clinical practice is urinary tract infections (UTIs). Limiting unnecessary antibiotic use and improving clinical care for many patients will result from accurate diagnosis and evidence-based treatment of UTIs. Crops and urine tests are useful for the diagnosis of UTIs; however, it is necessary to keep in mind their disadvantages. Due to the fact that most non-pregnant patients with asymptomatic bacteriuria&nbsp; do not require antibiotics and may even be harmful when prescribed, it is extremely important to distinguish true UTI from asymptomatic bacteriuria. The scope of UTI syndromes, such as acute uncomplicated cystitis, pyelonephritis, prostatitis and catheter-associated UTIs, determines the choice of antibiotics and the duration of their administration. Treatment methods also depend on the patient's immunosuppression and the characteristics of their genitourinary system. Therefore, patients with urological obstruction or patients receiving kidney transplantation may need a specialized management approach that includes working with various disciplines. Some preventive measures can be used for people prone to frequent UTIs, but there is often no universal method. Thus, urinary tract infection is very common among urology doctors. The frequency of this pathology does not decrease, despite the existing methods of diagnosis and treatment. There are conflicting opinions about the etiology and pathogenesis of the disease, early signs of diagnosis and risk factors.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5256 Features of the Clinical Course of Enterobiasis in Children 2024-06-20T08:50:53-04:00 Soliyeva Kamola Isomiddinovna author@gmail.co <p>Parasitic diseases constitute a significant part of infectious pathology, including in children. However, the massive spread of parasitic diseases is recorded in all regions of the world. The WHO expert assessment indicates that in terms of the number of patients, helminthiases are in 3rd place in the world, and malaria is in 4th place among all the most significant infectious and parasitic diseases.</p> 2024-06-20T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5190 Evaluation of Nurses’ Knowledge toward Human Immuno Deficiency 2024-06-17T15:11:30-04:00 Namaa Dawoud Salman namaa.Saleh2202m@conursing.uobaghdad.edu.iq Khalida Mohammed Khudur khalidam@conursing.uobaghdad.edu.iq <p><strong>Background:</strong> There are around 37 million people in the worldwide HIV population. HIV is mostly associated with homosexual behavior, with straight women in Sub-Saharan Africa experiencing the most severe impact. Nurses have a vital role in overseeing HIV/AIDS management, delivering care, and improving patient safety. Training courses and educational efforts are crucial for enhancing nurses' knowledge and attitudes. Additional study is required to comprehend the comprehension and participation of rural nurses in healthcare research.</p> <p><strong>Objective(s):</strong> This study aims to evaluate nurses' knowledge toward human Immuno deficiency.</p> <p>Methodology: A quasi-experimental design was conducted in 7 January 2024 to 7 May 2024, The research was carried out at Al Musayyib General Hospital and included 100 nursing personnel who were separated into two groups. There were 50 nurses who took part in a health education program, while another 50 nurses served as a control group by not engaging in the program. All nurses were from the night shift.</p> <p><strong>Results:</strong> Most nurses in both the research group (62%) and the control group (72%) were young, aged between 23 and under 30. Women comprised 66% of the study group and 54% of the control group. 58% of nurses in the study group were married, whereas 46% of nurses in the control group were unmarried. The majority of nurses resided in urban regions, with 82% in the study group and 86% in the control group. The assessment of HIV knowledge revealed an enhancement in the study group's general knowledge level from an average score of .28 in the pretest to a satisfactory level of .94 in the posttest. On the other hand, participants in the control group maintained a consistent level of knowledge, showing a little decrease from their pretest score (average score of 0.58) to their posttest score (average score of 0.50). Participants in the study group showed an increase in knowledge regarding HIV transmission techniques from an average score of 0.31 to 0.90, whereas negligible improvements were seen in the control group.</p> <p><strong>Conclusion:</strong> The research emphasizes differences, in nurses understanding of HIV. Nurses who underwent training showed progress in their HIV knowledge moving from a low level to a high level after the intervention. On the hand the control group, who didn't receive the training maintained only a moderate level of knowledge throughout the study with minor decreases in scores from before to after the intervention. These findings highlight how educational initiatives can improve nurses expertise in HIV related topics, which's essential, for their safety and the quality of treatment.</p> <p><strong>Recommendations:</strong> Institutions should organize regular HIV training sessions for nursing staff, customize educational resources, assess and review knowledge levels, promote peer learning, and broaden research scope to improve understanding of HIV care practices. This will help nurses improve their knowledge and make necessary adjustments to programs, ensuring effective HIV care.</p> 2024-06-21T00:00:00-04:00 Copyright (c) 2024 American Journal of Pediatric Medicine and Health Sciences (2993-2149) http://grnjournal.us/index.php/AJPMHS/article/view/5296 The clinical and laboratory characteristics of congenital pneumonia in newborns 2024-06-25T07:27:24-04:00 Shamsiev Furqat Muxitdinovich author@gmail.com Musajanova Ra’no Anvarbekovna author@gmail.com Ismoilova Shamsiya Soxibnazar qizi author@gmail.com Xudoynazarov Haydarqul Soxibnazar o’g’li author@gmail.com <p>It is said that the newborn a clinic for pneumonia in babies with a number of features and only with a hearth and breathing without signs of systemic inflammation can be manifested with a violation.Some researchers fever and tachypnea presence in newborns an important diagnostic sign of pneumonia they believe that. Pneumonia is inflammation of the lungs, an infectious disease of the lungs, an independent disease or a complication of other diseases.</p> 2024-06-23T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5307 Features of Rehabilitation Therapy for Patients with Symptomatic Epilepsy 2024-06-26T03:10:16-04:00 Fayzullaeva Vazira Khamidovna Author@gmail.co <p>At present, comprehensive rehabilitation and social integration of children with disabilities is one of the priorities of the state social policy of the Republic of Uzbekistan. However, cerebral palsy is also accompanied by the so-called optional symptoms of damage to the central nervous system, which, although not included in the mandatory pathological symptom complex, significantly complicate treatment and worsen the rehabilitation prognosis of the disease.</p> 2024-06-26T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5308 Study of the Effect of Various Drugs on Intestinal Microflora 2024-06-26T03:11:31-04:00 Hamidova Saodat Khikmatovna Author@gmail.co <p>The anal canal of the rat rectum is morphologically subdivided into the pre-sphincter region, the transition zone, the internal sphincter, the external sphincter, the space between the sphincters and the intersphincter zone.</p> <p>When examining the internal and external sphincters of the rectum, it was revealed that they form a complex combined formation. Changes in the wall of the anal canal of the rectum depend on the type and duration of exposure to the xenobiotic and the age of the animals. Xenobiotics affect both their formation and function. The results obtained further reveal the mechanism of occurrence of various disorders of the sphincter apparatus of the rectum in areas with a high content of xenobiotics, in particular copper sulfate and potassium rhodanide.</p> 2024-06-26T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5309 Characteristics of Dental Caries among Children 2024-06-26T03:12:45-04:00 Muxsinova Lola Anvarovna Author@gmail.co <p>In modern dentistry, despite the use of various methods of prevention and treatment of caries of dental hard tissues, it remains one of the most common diseases of dental hard tissues. There are hundreds of reasons that contribute to the development of caries in milk teeth. The most important of them socio-demographic, biological, dietary, hygienic and nutritional factors. In this case, the occurrence or attenuation of a number of conditions will later determine the early development of caries in children.</p> 2024-06-26T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5310 Optimal Treatment Method for Prurigo Patients with Neuropsychic Features 2024-06-26T03:17:26-04:00 Saitkulov Elyor Khalbaevich Author@gmail.co Azizov Bakhadir Sadikovich Author@gmail.co Nurmatova Iroda Baxkhtiyarovna Author@gmail.co Ayupova Shakhnoza Tokhirjon-qizi Author@gmail.co <p>Given the problematic nature of comorbid disorders especially if patients with prurigo and neuropsychiatric disorders, the article considers the possibility of using tranquilizers for the treatment of prurigo. And also for local treatment the use of tincture of chilli pepper in long-term treatment purposes, which will save money ball.</p> 2024-06-26T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5311 Assessment of Nutrition and Importance of School Conditions to the Health of Students Studying in Urban and Rural Conditions 2024-06-26T03:19:41-04:00 Urokova Kamola Khamidovna Author@gmail.co <p>One of the main factors determining children’s health is nutrition. During their education in secondary schools, students perform not only mental but also physical activities. During this period, students feel the need for foods with high energy value due to high energy spending. Improper organization of children’s nutrition in secondary schools reduces their educability and increases the body's susceptibility to various diseases.</p> 2024-06-26T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5336 Optimizing the Treatment of Purulent Inflammations of the Face and Oral Cavity 2024-06-27T07:40:47-04:00 Sabirov Shuxrat Solijonovich author@gmail.co <p>As a rule, the standard treatment of most purulent-inflammatory diseases of the maxillofacial region involves surgical intervention followed by the use of antibacterial and symptomatic therapy. At the same time, they do not always resort to the correction of immunometabolic disorders with the help of drugs and physiotherapeutic methods of treatment.</p> 2024-06-26T00:00:00-04:00 Copyright (c) 2024 http://grnjournal.us/index.php/AJPMHS/article/view/5337 Studying the Prevalence of Psoriasis 2024-06-27T08:18:42-04:00 Nurova Gulxumor author@gmail.co Ubaydullaevna author@gmail.co <p>Psoriasis is characterized by the presence of two peaks of incidence and, in accordance with this, two types of dermatosis: The first type is characterized by a hereditary predisposition and early onset of the disease (usually at 15-25 years), the second type is characterized by a late onset of the disease (after 40 years) and the absence of genetic predisposition [2, 3, 5, 8, 11]. A large amount of data has been accumulated on the presence of an association of type 1 psoriasis with hla antigens of classes I and II [4, 10, 12, 13, 15]. 8 loci have been identified to date predisposition to psoriasis, which mapped on 8 chromosomes and designated psors1—psors8. it was established that the locus psors1, located on the short arm of the 6th chromosomes (6p21.3), is the main one, because it contains several linked genes actively expressed in skin keratinocytes. This locus represents the area in which there are five genes [hla-c, tcf19(sc1), otf3 (pouf5f1), hcr(pg8), cdsn], from of which two (hcr u cdsn) have an association with psoriasis [6, 11—15]. However with what type psoriasis, these genes are associated is not clear, which determined the need to carry out of this study.</p> 2024-06-26T00:00:00-04:00 Copyright (c) 2024