The Correlation between ABO Blood Groups and the IFN-Γ Levels in COVID 19 Infected Patients

Abstract

This investigation was conducted in the Iraqi province of Wasit in collaboration with the microbiology units of Fairouz Hospital and Alzahraa Hospital. This study's objectives were to assess interferon (IFN)-γ serum levels and this cytokine's protective role based on the ABO blood types among SARS-CoV-2 infected individuals. Samples were gathered in the province of Wasit from various locations. It had 22 healthy individuals as a control group and 66 blood samples from Iraqi patients suffering with COVID-19. The study was carried out between January and April of 2024, with both groups' ages ranging from 14 to 72. There were three patient classifications: mild (22 patients), moderate (22 patients), and severe (22 patients). All participants' serum samples were taken, and ELISA (enzyme-linked immunosorbent assay) was used to measure the levels of cytokines using monoclonal antibodies (Anti-A, B, and D). All of these tools are easily accessible in a blood test tool set. ( AntiSera ABD Blood Grouping Reagent BIOLAB-India). The ANOVA test shows that mean level was statistically not significant difference( p-value 0.649) for concentration of interferon gamma according to the blood groups.