Structural Changes in Liver Tissue for Simulated Skin Burns of Rats

Abstract

Immediately after a thermal burn, significant qualitative and quantitative changes in metabolic processes occur in the body. The work reveals the histopathological features of the structure of hepatocytes in the liver tissue of rats both normally and under the influence of a simulated thermal burn. The morphological characteristics of the liver of experimental groups of rats treated with various drugs were studied. It has been established that under conditions of burn exposure in rats, significant hemodynamic disturbances, numerous small hemorrhages, and swelling and necrosis of small areas of the organ parenchyma, fatty hepatosis. Identification of pathomorphological transformations of organs in burn wounds of the skin will allow optimizing an integrated approach to the treatment of burn disease.