Pancreas in a Patient with Diabetes Mellitus the Current State of the Issue

Abstract

To date, DM is one of the most common non-communicable human diseases after cardiovascular and oncological pathology, leading to disability and, often, fatal outcomes. Exocrine pancreatic insufficiency (ENPJ) is a common name for the malabsorption process caused by inadequate production and reduced activation of enzymes of pancreatic acinar cells, such as amylase, lipase and protease, necessary for digestion. According to numerous studies, up to 14% of the adult population in European countries has a violation of glucose tolerance, 7% of the surveyed revealed violations of fasting glucose levels, and 3-4% found a combination of these violations. The prevalence of ENP in patients with type 1 diabetes mellitus (DM1), according to many authors, varies from 25 to 59%, which is determined by the data of pancreatic elastase-1 (PE-1).